Immunization & Vaccination Status Blood Test (Basic) | Quest®

Vaccination Status Test Panel — Basic

Test the levels of antibodies for 8 infectious diseases from infection or vaccination. The infectious disease markers measured in this panel are tetanus, diphtheria, pertussis (whooping cough), measles, mumps, rubella, varicella zoster virus (chickenpox & shingles), and polio. Read more

Test details

Preparation:

You do not need to do anything special to prepare for the sample collection. Fasting is not required for this test.

Test type: In Person

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$259.00

+ $6.00 Physician Service Fee

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About the Test

By measuring antibody levels, know whether you have been exposed to or vaccinated for tetanus, diphtheria, pertussis measles, mumps, rubella, varicella zoster virus, and polio. This blood test for antibodies or vaccination status is useful for those who are unsure about a prior infection or require proof of immunity for school, work, or travel.

Notes: This test does not confirm an active infection for any of the diseases. The results of this test alone do not constitute any diagnoses. A formal diagnosis of any infection must be made by a clinician. This test cannot definitively determine immunity status for tetanus, diphtheria, pertussis, varicella zoster virus, polio, and meningitis but it can detect antibodies from previous infection or vaccination.

With Quest, you can buy an immunization antibody test online and get testing at a nearby location – no doctor’s visit required.

This may be right for you if:

You’re unsure whether you’ve had tetanus, diphtheria, pertussis (whooping cough), measles, mumps, rubella, chickenpox, shingles, polio, or any related vaccinations (Tdap, MMR, VZV, etc.) for these diseases in the past
You attend a school or work in a job that requires proof of immunity to tetanus, diphtheria, pertussis, measles, mumps, rubella, varicella, and/or polio. This test cannot definitively determine immunity status for tetanus, diphtheria, pertussis, varicella zoster virus, and polio, but it can detect antibodies from previous infection or vaccination
You’re planning an international trip
You live in a community where an outbreak of one of these infectious diseases is occurring, and you want to help assess your vaccination status
You are a close family member or caregiver for a newborn who is particularly vulnerable to whooping cough¹

This test may not be right for you if:

You are sick, and you want to determine whether you have an active tetanus, diphtheria, pertussis, measles, mumps, rubella or polio infection (see Signs & Symptoms section below)
You are interested in learning the source of your antibody levels

If you have questions about whether this test is right for you, please contact your healthcare provider.

This test measures blood levels of antibodies to the following diseases to assess for evidence of previous infection or vaccination.

Tetanus, or “lockjaw," is caused by Clostridium tetani bacteria. These bacteria can be found all over the environment, including in dirt, soil and manure. If it enters the body, usually through broken skin from an injury, it makes a toxin that causes painful muscle spasms and can cause a person’s neck/jaw muscles to lock. Other parts of the body can also be affected by these muscle spasms. Tetanus is not contagious and cannot be spread from person to person. This test measures tetanus antitoxoid antibodies.

Diphtheria is caused by strains of Corynebacterium diphtheriae bacteria. Diphtheria is highly contagious and spreads through the air, usually by coughing or sneezing, and affects the nose and/or throat. People can also get sick with diphtheria by touching infected open sores. This test measures diphtheria antitoxoid antibodies.

Pertussis, also known as "whooping cough," is caused by Bordetella pertussis bacteria. It is a highly contagious, respiratory infection that causes uncontrollable coughing. Whooping cough can affect all ages, but it can be especially severe in unvaccinated babies. This test measures Bordetella pertussis IgG antibodies.

Measles, also known as rubeola, is a highly contagious viral infection that occurs primarily in children. Measles infection causes fever, irritability, cough, respiratory illness, pink eye (conjunctivitis) and tiny white spots inside the mouth (Koplik spots) followed by the appearance of a characteristic flat, red rash. The rash usually starts on the face and spreads all over the body. This test measures measles (rubeola) IgG antibodies.

Mumps is a highly contagious, viral infection that typically begins with a high fever and flu-like symptoms (headache, muscle aches, tiredness, and loss of appetite). The mumps virus may cause inflamed salivary glands, puffy cheeks, and a tender, swollen jaw. However, some people with mumps infection may appear without symptoms. This test measures mumps virus IgG antibodies.

Rubella, also known as German measles, is a contagious, viral infection. It may appear mild with a fever, swollen glands, aching joints (especially in young women), or more severely with joint pain, swollen lymph nodes, fatigue, and a distinctive red rash on the face that spreads downward to the rest of the body. Some people with a rubella infection may appear without symptoms. In pregnant women, rubella can cause a miscarriage and birth defects. This test measures rubella IgG antibodies.

The varicella zoster virus (VZV) is a highly contagious virus that can cause both varicella (chickenpox) and herpes zoster (shingles). Chickenpox is a contagious viral disease characterized by an itchy, blister-like rash. Initially, the rash appears on the chest, back, and face and then spreads across the body. Most chickenpox and shingles infections resolve without issues. The disease can be more severe and long-lasting in people with weakened immune systems, such as those living with HIV/AIDS or who have undergone organ transplantation. After you have chickenpox, most people become immune to the virus for the rest of their lives, and they usually don’t get chickenpox again. However, the virus stays inactive in your body and can reactivate as shingles later in life. Shingles can cause a viral outbreak of a painful rash or blisters on the skin. Unlike chickenpox, shingles is not contagious. However, VZV is contagious and if you have shingles, you can spread the virus to another person, and they may develop chickenpox. Prior to VZV vaccination, chickenpox was very common in the United States. The chickenpox vaccine uses a small amount of live VZV virus to help protect against chickenpox in individuals 12 months and older. After being exposed to VZV through infection or vaccination, a person's immune system produces antibodies to help fight against the viral infection. This test measures the level of IgG antibodies in the blood produced in response to VZV due to a previous infection or vaccine.

Polio, or poliomyelitis, is a disabling and potentially deadly disease. It is caused by the poliovirus. The virus spreads from person to person and can infect a person’s spinal cord, causing paralysis (can’t move parts of the body). This test is for type 1 and type 3 poliovirus antibodies.

This test is not intended to and should not be used to determine whether you have an active infection. Signs and symptoms of these diseases are different and may include the following (listed below). If you have any of these symptoms, this test is not right for you. If you experience these symptoms, contact a healthcare provider to seek medical attention. If you are having a medical emergency, please seek emergency medical care or call 911.

Jaw cramping or spasms, or “lockjaw”
Sudden, involuntary muscle spasms – often in the stomach
Painful muscle stiffness all over the body
Trouble swallowing
Headache
Fever and sweating
Changes in blood pressure and heart rate
Seizures

Weakness
Sore throat
Fever
Swollen glands in the neck

Severe coughing fits
Vomiting during or after coughing fits
Fatigue after coughing fits
Runny or stuffed-up nose
Fever
Difficulty breathing

High fever
Cough
Runny nose
Body aches
Feeling weak or tired
Pink eye (conjunctivitis)
Tiny white spots inside the mouth (Koplik spots)
Flat red spots on the face and neck that become more solid as they spread across the body (measles rash)

Fever
Chills
Headache
Fatigue
Muscle aches
Loss of appetite
Painful swelling of salivary glands located between the ear and jaw (parotitis)
Puffiness of the cheeks
Difficulty chewing

Fever
Headache
Cough
Runny nose
Ear infection
Body aches
Joint pain and stiffness
Fatigue
Swollen lymph nodes
Feeling weak or tired
Conjunctivitis
Inflammation of the brain (encephalitis)

Rash
Fever
Fatigue
Headache
Loss of appetite
An extremely itchy blister-like rash that usually appears on the chest, back, and face and then spreads across the body
Fluid-filled blisters that eventually turn into scabs

Rash
Fever
Fatigue
Headache
Chills
Upset stomach
Sensitivity to bright light (photophobia)
Severe pain, itching, or tingling in the area where the rash develops
A blistering rash that typically develops on the left or right side of the body, and, in some cases, on one side of the face
Fluid-filled blisters that eventually dry and crust over

Fever
Fatigue
Headache
Vomiting
Stiffness in neck and pain in limbs
Paralysis

You must be 18 years of age or older to purchase a test on questhealth.com. Purchases not permitted in: AK, AZ, HI.

You do not need to do anything special to prepare for the sample collection. Fasting is not required for this test.

After you provide your specimen, it generally takes a few business days to process and release your test results. However, processing times may vary. Your test results will be available in a clear and easy-to-read report. Independent physicians are available to discuss questions or concerns you may have regarding your results.

How it works

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Access results online as soon as they’re available. You will be emailed when they are ready. Discuss your results with an independent physician at no extra cost. Treatment options may be available.

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After you make a purchase, register your test and Quest Mobile will contact you to schedule an in-home sample collection appointment.

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A Quest Mobile phlebotomist will collect your sample and deliver it to Quest Diagnostics.

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Access results online as soon as they’re available. You will be emailed when they are ready. Discuss your results with an independent physician at no extra cost. Treatment options may be available.

Compare Tests

And find the right tests for you.

Test For	Vaccination Status Test Panel — Basic	Vaccination Status Test Panel — Expanded
Tetanus
Diphtheria
Pertussis (Whooping Cough)
Measles
Mumps
Rubella
Varicella zoster virus
Polio
Hepatitis A
Hepatitis B
Meningitis
	$259.00	$299.00 Learn More

Vaccination Status Test Panel — Basic	Vaccination Status Test Panel — Expanded
Tetanus
Diphtheria
Pertussis (Whooping Cough)
Measles
Mumps
Rubella
Varicella zoster virus
Polio
Hepatitis A
Hepatitis B
Meningitis
$259.00	$299.00 Learn More

FAQs

How do these diseases spread?

Tetanus is not contagious and is spread into someone’s body through broken skin, usually from injuries like punctures, burns, scrapes, and crushes. It can also infect someone’s body through breaks in the skin caused by surgical procedures, insect bites, dental infections, chronic sores and infections, and more.

Diphtheria and pertussis are both highly contagious and spread through the air by coughing, sneezing, or sharing breathing space. Diphtheria can also be spread by touching infected open sores.

Measles, mumps, and rubella viruses are spread via direct contact with, or droplets shed from respiratory secretions, saliva, or mucus from the throat, mouth, or nose of infected individuals. They are easily transmitted from person to person through coughing or sneezing.

Chickenpox is spread through contact with the blisters, saliva or mucus of an infected person but can also be transmitted through the air by coughing and sneezing. Shingles is spread during the blister-phase of the rash, as the fluid is filled with virus particles. Direct contact with the rash is the most common method of infection, but breathing in virus particles in the air can also occur.

Polio is usually spread through oral contact with stool, or less commonly, droplets from a sneeze or cough from an infected person. Some common ways of contracting polio are through eating contaminated food, drinking contaminated water or putting contaminated objects in your mouth.

What do I do if the results show that I do not have immunity?

If your test results detect antibodies below a certain level, it may indicate that you are at an increased risk for infection if you are exposed to the virus or bacteria that cause these diseases. You should share your results with your healthcare provider, who can help you decide on next steps.

Do I need a booster shot or another vaccination?

If your test results do not show evidence of immunity against these diseases, or if you have not received the recommended doses of the vaccine, it is important to speak with your healthcare provider to determine if additional boosters may be beneficial.

Can I be infected with these diseases if the results are normal?

People who receive the recommended doses of the Tdap vaccine are usually considered protected for approximately 10 years. However, a few people may still become infected if they are exposed to the bacteria that cause these diseases.

People who receive the recommended dose of the MMR vaccine are usually considered protected for life against measles and rubella. However, a small number of people may still become infected if they are exposed to the viruses that cause these diseases.

People who receive the recommended doses of the chickenpox and shingles vaccines are usually considered to have lifelong immunity. However, those at higher risk for shingles, as well as those with weakened immune systems, may need additional vaccination.

People who receive the recommended doses of the polio vaccine are usually considered to have lifelong immunity. However, those at increased risk of exposure may receive 1 lifetime dose of a booster vaccine.

What is the difference between the Tdap, DTaP, and Td vaccines?

Tdap provides protection against tetanus, diphtheria, and pertussis and is given to those who are 7 years or older.
DTaP provides protection against diphtheria, tetanus, and pertussis and is given to those who are younger than 7 years old.
Td provides protection against tetanus and diphtheria and is given to those who should not get pertussis vaccines due to allergies or medical conditions.

Can I get shingles if I've never had chickenpox?

You can’t get shingles if you have never had chickenpox.

Chickenpox and shingles are both caused by VZV. When a person who has never had chickenpox encounters someone who has shingles, they may contract chickenpox; however, they cannot get shingles. After a person becomes infected with chickenpox, VZV remains inactive in the body. As a person ages or in those living with a weakened immune system, VZV may reactivate, causing shingles.

Can I use my FSA or HSA funds to purchase tests on questhealth.com?

You may be able to use your FSA or HSA funds to purchase lab tests at questhealth.com. Please review your FSA/HSA plan or check with a tax professional to confirm specific requirements for individual eligibility.

Our references

References

Centers for Disease Control and Prevention. Vaccines for Family and Caregivers. Accessed March 18, 2024. https://www.cdc.gov/vaccines/pregnancy/family-caregivers.html
Centers for Disease Control and Prevention. Tdap Vaccine Information Statement. Accessed March 18, 2024. https://www.cdc.gov/vaccines/hcp/vis/vis-statements/tdap.html
Centers for Disease Control and Prevention. Tetanus Symptoms and Complications. Accessed March 18, 2024. https://www.cdc.gov/tetanus/about/symptoms-complications.html
Centers for Disease Control and Prevention. Diphtheria Signs and Symptoms. Accessed March 18, 2024. https://www.cdc.gov/diphtheria/about/symptoms.html
Centers for Disease Control and Prevention. Pertussis Signs and Symptoms. Accessed March 18, 2024. https://www.cdc.gov/pertussis/about/signs-symptoms.html
Centers for Disease Control and Prevention. Diphtheria, Tetanus, and Whooping Cough Vaccination: What Everyone Should Know. Accessed March 18, 2024. https://www.cdc.gov/vaccines/vpd/dtap-tdap-td/public/index.html
Chickenpox (varicella zoster infection) (ny.gov)
https://www.health.ny.gov/diseases/communicable/shingles/fact_sheet.htm
Chickenpox (Varicella) Vaccine Information Statement | CDC
Poliomyelitis (who.int)
Polio | Disease Directory | Travelers' Health | CDC
Polio Vaccination | Polio | CDC

Tests purchased on questhealth.com are only for individuals who intend to pay directly for testing and do not want to submit a claim for reimbursement under their health insurance.

Vaccination Status Test Panel — Basic